Top latest Five ceesdekker Urban news

Nanotechnology features a range of possibilities to contribute to biology. Listed here I will current illustrations wherever nanofabrication – a chance to make confined buildings with Proportions at will – is used to examine the biophysics of single molecules and cells. I'll existing some illustrations from our lab:

Our team research bacterial mobile division which is aiming to constitute a ‘bottom up biology’ in artificial cells that could autonomously divide. Our major curiosity lies in mobile division, chromatin framework, and spatial Handle.

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I'm able to barely consider how I, for a geneticist, would manage to master elementary physics, let alone compete at the top. How did you go over it?

2010, formulated a completely new way (‘wedging transfer’) to manipulate nanostructures; very first report of DNA translocation by way of graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into good-point out nanopores

Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en met 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.

We use nanofabricated microfluidic buildings to sample spatial boundaries for microbes and biomimetic vesicles with reconstituted protein networks which evaluate the elemental job of spatial confinement at the molecular and mobile level. Our tasks consist of the following:

Dynamic ParB–DNA interactions initiate and keep a partition condensate for bacterial chromosome segregation

Let's say, in place of working with traditional major-down silicon electronics, transistors may be built from The underside up using solitary natural and organic molecules since the switching features? This idea, which turned the basis of nowadays’s field of molecular electronics, 1st emerged in the seventies.

There was just one trouble though — we didn't notice any measurable electrical conduction from The one polymer molecules. We concluded that at The one-molecule amount, conducting polymers were being actually not this kind of fantastic conductors, which was fairly disappointing. We Hence broadened our watch to test to search out additional promising molecules.

An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes

1999, initial measurement with the wavefunction of single molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive evidence for a new Luttinger description of interacting electrons in nanotubes

2005, discovery of the mechanism of DNA uncoiling by topoisomerase https://www.ceesdekker.net enzymes; discovery of extensive-assortment conformational changes in Mre11/DNA mend complexes; and to start with power measurements over a DNA molecule in a nanopore

‘I'm pushed by marvel and queries. On a fabric stage I obtain responses in physics, but I encounter my deepest joy with God. That faith also drives my science and how I handle men and women.